An analysis of balancing of V6 engines equipped with split-pin crankshafts with any cylinder bank angle based on the mathematical relations derived in the paper was carried out. A comparison of the quality of their balancing with engines equipped with common-pin crankshafts was also carried out. The bank angle ranges beneficial for balancing of moments of inertia forces in reciprocating motion were determined. A mathematical relation on the optimum value of the main counterweights in the function of the cylinder bank angle was derived as well. The advantages of the split-pin crankshafts from the point of view of balancing were also indicated also.